Alper, Phil: search on Z-Library

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1

Design and Synthesis of New Aminoglycoside Antibiotics Containing Neamine as an Optimal Core Structure: Correlation of Antibiotic Activity with in Vitro Inhibition of Translation

Greenberg, William A., Priestley, E. Scott, Sears, Pamela S., Alper, Phil B., Rosenbohm, Christoph, Hendrix, Martin, Hung, Shang-Cheng, Wong, Chi-Huey

Journal:

Journal of the American Chemical Society

Year:

1999

Language:

english

File:

PDF, 209 KB

english, 1999

2

Frontispiece: Photoinduced Rearrangement of Dienones and Santonin Rerouted by Amines

Zhang, Zhipeng, Ratnikov, Maxim, Spraggon, Glen, Alper, Phil B.

Journal:

Angewandte Chemie International Edition

Year:

2018

File:

PDF, 6.63 MB

2018

3

Discovery of Tropifexor (LJN452), a Highly Potent Non-Bile Acid FXR Agonist for the Treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis (NASH)

Tully, David C., Rucker, Paul V, Chianelli, Donatella, Williams, Jennifer, Vidal, Agnes, Alper, Phil B., Mutnick, Daniel, Bursulaya, Badry, Schmeits, James, Wu, Xiangdong, Bao, Dingjiu, Zoll, Jocelyn,

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.38 MB

english, 2017

4

Hydroxyamine als neues Motiv für die molekulare Erkennung von Phosphodiestern: Hinweise auf Aminoglycosid-RNA-Wechselwirkungen

Martin Hendrix, Phil B. Alper, Dr. E. Scott Priestley, Prof. Dr. Chi-Huey Wong

Journal:

Angewandte Chemie

Year:

1997

Language:

german

File:

PDF, 551 KB

german, 1997

5

ChemInform Abstract: Facile, Novel Methodology for the Synthesis of Spiro[pyrrolidin-3,3′-oxindoles]: Catalyzed Ring Expansion Reactions of Cyclopropanes by Aldimines.

Phil B. Alper, Christiane Meyers, Andreas Lerchner, Dionicio R. Siegel, Erick M. Carreira

Journal:

Year:

2000

File:

PDF, 36 KB

2000

6

Practical Synthesis and Elaboration of Methyl 7-Chloroindole-4-carboxylate

Alper, Phil B., Nguyen, KhanhLinh T.

Journal:

Journal of Organic Chemistry

Year:

2003

Language:

english

File:

PDF, 59 KB

english, 2003

7

Synthesis and evaluation of arylaminoethyl amides as noncovalent inhibitors of cathepsin S. Part 3: Heterocyclic P3

David C. Tully, Hong Liu, Phil B. Alper, Arnab K. Chatterjee, Robert Epple, Michael J. Roberts, Jennifer A. Williams, KhanhLinh T. Nguyen, David H. Woodmansee, Christine Tumanut, Jun Li, Glen Spraggon

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 212 KB

english, 2006

8

Homocarbonates as Substrates for the Enantioselective Enzymatic Protection of Amines

Orsat, Bernard, Alper, Phil B., Moree, Wilna, Mak, Ching-Pong, Wong, Chi-Huey

Journal:

Journal of the American Chemical Society

Year:

1996

Language:

english

File:

PDF, 146 KB

english, 1996

9

Photoinduced Rearrangement of Dienones and Santonin Rerouted by Amines

Zhang, Zhipeng, Ratnikov, Maxim, Spraggon, Glen, Alper, Phil B.

Journal:

Angewandte Chemie International Edition

Year:

2017

Language:

english

File:

PDF, 1.69 MB

english, 2017

10

Facile, Novel Methodology for the Synthesis of Spiro[pyrrolidin-3,3′-oxindoles]: Catalyzed Ring Expansion Reactions of Cyclopropanes by Aldimines

Phil B. Alper, Christiane Meyers, Andreas Lerchner, Dionicio R. Siegel, Erick M. Carreira

Journal:

Angewandte Chemie International Edition

Year:

1999

Language:

english

File:

PDF, 112 KB

english, 1999

11

Discovery of potent, orally bioavailable in vivo efficacious antagonists of the TLR7/8 pathway

Alper, Phil B., Jonathan, Deane, Betschart, Claudia, Buffet, David, Collignon Zipfel, GÃ©raldine, Gordon, Perry, Hampton, Janice, Hawtin, Stuart, Ibanez, Maureen, Jiang, Tao, Junt, Tobias, Knoepfel, T

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2020

File:

PDF, 406 KB

2020

12

Synthesis and SAR of arylaminoethyl amides as noncovalent inhibitors of cathepsin S: P3 cyclic ethers

David C. Tully, Hong Liu, Arnab K. Chatterjee, Phil B. Alper, Robert Epple, Jennifer A. Williams, Michael J. Roberts, David H. Woodmansee, Brian T. Masick, Christine Tumanut, Jun Li, Glen Spraggon, Mi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 185 KB

english, 2006

13

Photoinduced Rearrangement of Dienones and Santonin Rerouted by Amines

Zhang, Zhipeng, Ratnikov, Maxim, Spraggon, Glen, Alper, Phil B.

Journal:

Angewandte Chemie

Year:

2017

Language:

english

File:

PDF, 1.63 MB

english, 2017

14

Arylaminoethyl carbamates as a novel series of potent and selective cathepsin S inhibitors

David C. Tully, Hong Liu, Arnab K. Chatterjee, Phil B. Alper, Jennifer A. Williams, Michael J. Roberts, Daniel Mutnick, David H. Woodmansee, Thomas Hollenbeck, Perry Gordon, Jonathan Chang, Tove Tuntl

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 157 KB

english, 2006

15

Substrate specificity of the human proteasome

Jennifer L Harris, Phil B Alper, Jun Li, Martin Rechsteiner, Bradley J Backes

Journal:

Chemistry & Biology

Year:

2001

Language:

english

File:

PDF, 3.55 MB

english, 2001

16

Frontispiz: Photoinduced Rearrangement of Dienones and Santonin Rerouted by Amines

Zhang, Zhipeng, Ratnikov, Maxim, Spraggon, Glen, Alper, Phil B.

Journal:

Angewandte Chemie

Year:

2018

File:

PDF, 6.61 MB

2018

17

Target-Based Identification and Optimization of 5-Indazol-5-yl Pyridones as Toll-like Receptor 7 and 8 Antagonists Using a Biochemical TLR8 Antagonist Competition Assay

Knoepfel, Thomas, Nimsgern, Pierre, Jacquier, SÃ©bastien, Bourrel, Marjorie, Vangrevelinghe, Eric, Glatthar, Ralf, Behnke, Dirk, Alper, Phil B., Michellys, Pierre-Yves, Deane, Jonathan, Junt, Tobias,

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 6.38 MB

2020

18

Metal catalyzed diazo transfer for the synthesis of azides from amines

Phil B Alper, Shang-Cheng Hung, Chi-Huey Wong

Journal:

Tetrahedron Letters

Year:

1996

Language:

english

File:

PDF, 218 KB

english, 1996

19

Probing the Specificity of Aminoglycoside−Ribosomal RNA Interactions with Designed Synthetic Analogs

Alper, Phil B., Hendrix, Martin, Sears, Pamela, Wong, Chi-Huey

Journal:

Journal of the American Chemical Society

Year:

1998

Language:

english

File:

PDF, 462 KB

english, 1998

20

Transmission Intensity and Its Relationship to Infection and Disease Due to Wuchereria bancrofti in Papua New Guinea

James W. Kazura, Moses Bockarie, Neal Alexander, Robert Perry, Frances Bockarie, Henry Dagoro, Zachary Dimber, Phil Hyun and Michael P. Alpers

Journal:

The Journal of Infectious Diseases

Year:

1997

Language:

english

File:

PDF, 1.15 MB

english, 1997

21

Design and synthesis of arylaminoethyl amides as noncovalent inhibitors of cathepsin S. Part 1

Hong Liu, David C. Tully, Robert Epple, Badry Bursulaya, Jun Li, Jennifer L. Harris, Jennifer A. Williams, Ross Russo, Christine Tumanut, Michael J. Roberts, Phil B. Alper, Yun He, Donald S. Karanewsk

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 292 KB

english, 2005

22

Eine neuartige Methode zur Synthese von Spiro[pyrrolidin-3,3′-oxindolen]: katalysierte Ringerweiterung von Cyclopropanen mit Aldiminen

Phil B. Alper, Christiane Meyers, Andreas Lerchner, Dionicio R. Siegel, Erick M. Carreira

Journal:

Angewandte Chemie

Year:

1999

Language:

german

File:

PDF, 90 KB

german, 1999

23

Discovery and biological evaluation of benzo[a]carbazole-based small molecule agonists of the thrombopoietin (Tpo) receptor

Phil B. Alper, Thomas H. Marsilje, Daniel Mutnick, Wenshuo Lu, Arnab Chatterjee, Michael J. Roberts, Yun He, Donald S. Karanewsky, Donald Chow, Jianmin Lao, Andrea Gerken, Tove Tuntland, Bo Liu, Jonat

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 196 KB

english, 2008

24

Spatial variation ofAnopheles-transmittedWuchereria bancroftiandPlasmodium falciparuminfection densities in Papua New Guinea

Neal D Alexander, Rana A Moyeed, Phil J Hyun, Zachary B Dimber, Moses J Bockarie, Julian Stander, Bryan T Grenfell, James W Kazura, Michael P Alpers

Journal:

Filaria Journal

Year:

2003

Language:

english

File:

PDF, 501 KB

english, 2003

25

Hydroxyamines as a New Motif for the Molecular Recognition of Phosphodiesters: Implications for Aminogloycoside–RNA Interactions

Martin Hendrix, Phil B. Alper, Dr. E. Scott Priestley, Prof. Dr. Chi-Huey Wong

Journal:

Angewandte Chemie International Edition

Year:

1997

Language:

english

File:

PDF, 518 KB

english, 1997

26

Discovery of structurally novel, potent and orally efficacious GPR119 agonists

Alper, Phil, Azimioara, Mihai, Cow, Christopher, Mutnick, Daniel, Nikulin, Victor, Michellys, Pierre-Yves, Wang, Zhiliang, Reding, Esther, Paliotti, Michael, Li, Jing, Bao, Dingjiu, Zoll, Jocelyn, Kim

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 1.52 MB

english, 2014

27

Transmission Intensity and Its Relationship to Infection and Disease Due to Wuchereria bancrofti in Papua New Guinea

Kazura, James W., Bockarie, Moses, Alexander, Neal, Perry, Robert, Bockarie, Frances, Dagoro, Henry, Dimber, Zachary, Hyun, Phil, Alpers, Michael P.

Journal:

The Journal of Infectious Diseases

Year:

1997

Language:

english

File:

PDF, 129 KB

english, 1997

28

Novel tricyclic pyrazolopyrimidines as potent and selective GPR119 agonists

Azimioara, Mihai, Alper, Phil, Cow, Christopher, Mutnick, Daniel, Nikulin, Victor, Lelais, Gerald, Mecom, John, McNeill, Matthew, Michellys, Pierre-Yves, Wang, Zhiliang, Reding, Esther, Paliotti, Mich

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 851 KB

english, 2014

29

Optimization of small molecule agonists of the thrombopoietin (Tpo) receptor derived from a benzo[a]carbazole hit scaffold

Thomas H. Marsilje, Phil B. Alper, Wenshuo Lu, Daniel Mutnick, Pierre-Yves Michellys, Yun He, Donald S. Karanewsky, Donald Chow, Andrea Gerken, Jianmin Lao, Min-Ju Kim, H. Martin Seidel, Shin-Shay Tia

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 225 KB

english, 2008

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